Highlighted publications

"Mechanical force is used to probe π–π interactions within individual perylene diimide dimers by AFM-based force spectroscopy. Passive force spectroscopy quantifies their lifetimes under load and capture their dissociation pathways, providing insight into the energy landscape of noncovalent assemblies."
Angewandte Chemie Int. Ed. 2026

Single-molecule force spectroscopy shows that side chain interactions govern the mechanochemical response of polypeptide a- helices and prevent the formation of b-sheets

Mechanical tightening of a synthetic molecular knot

Highlight in Nature

Single-molecule mechanics of synthetic aromatic amide helices: Ultrafast and robust non-dissipative winding

Real-Time Fluctuations in Single-Molecule Rotaxane Experiments Reveal an Intermediate Weak Binding State during Shuttling

Viologen Tweezers to Probe the Force of Individual Donor-Acceptor Pi-Interactions

Synthetic oligorotaxanes exert high forces when folding under mechanical load

Dynamic force spectroscopy of oligorotaxane foldamers

Molecular Manipulation with Atomic Force Microscopy

A single synthetic small molecule that generates force against a load

Mechanochemistry: targeted delivery of single molecules