Molecular recognition
Molecular recognition between biological or synthetic species and between biological species and surfaces
The research activities of the group are concerned with the development of probes and technologies to interface single small functional molecules for AFM-based single-molecule force spectroscopy. For 15 years, we have developed the first examples of single-molecule force spectroscopy on small synthetic molecules to study their operation.
The expertise covers the development of strategies for the chemical modification of AFM tips and for the chemical coupling between tips and surfaces to detect intra- or intermolecular forces, and probe individual molecules. Tools to probe chemical processes, trigger and control them, and detect the induced mechanical response in situ and in real time are developed.